Medication
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Benefits
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Common Side Effects
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Notes
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Metformin
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May enhance healthspan and extend lifespan (source, source)
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Delay or prevent type 2 diabetes
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Help with weight loss (source)
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Reduce blood glucose levels
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Increase insulin sensitivity (source)
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Improve prognosis for cancer patients and may even help prevent cancer (source, source)
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Help with cardiovascular disease (source, source)
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Decrease inflammation (source)
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Reduce risk of cognitive impairment and dementia (source, source)
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Ease negative effects of stopping testosterone replacement therapy (source)
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Metformin may decrease vitamin B12 absorption, which can rarely cause anemia. Vitamin B12 supplementation may be recommended.
Metformin is FDA-approved for type 2 diabetes, but multiple third party studies have shown additional benefits and it may be prescribed for “off-label” use. While many of the studies used animal models and have not been proven in humans yet, clinical trials are ongoing (source).
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Glutathione
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Abdominal cramps
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Increased flatulence
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Loose stools
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Rotten egg (sulfur) taste in mouth
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Flushing, redness, swelling, or bruising at the injection site
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Multiple third party studies have shown the health benefits of glutathione. While many of the studies used animal models and have not been proven in humans yet, clinical trials are ongoing.
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NAD+
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May enhance healthspan and extend lifespan (source, source)
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Boost strength and physical performance (source)
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Help with weight loss (source)
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May delay neurodegenerative diseases (source, source, source)
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Improve blood vessel function and blood flow while reducing elastic artery stiffness (source)
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Reduce oxidative stress and inflammation (source), which is linked to serious diseases like cancer (source)
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Protect vital organs like the liver and kidneys (source)
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Support immune system (source)
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Headache
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Shortness of breath
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Constipation
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Increased plasma bilirubin
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Nausea
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Brain fog
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Cramping during therapy
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Redness, swelling, or bruising at the injection site
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Multiple third party studies have shown the health benefits of NAD+. While many of the studies used animal models and have not been proven in humans yet, clinical trials are ongoing.
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Vitamin B12 (Methylcobalamin)
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Supports central nervous system function, red blood cell formation, and DNA synthesis (source)
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Treats pernicious anemia from vitamin B12 deficiency, which can cause nerve damage and increases risk of stomach cancer (source)
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Benefits mood by reducing stress (source)
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Reduces risk of vision loss from age-related macular degeneration when taken with folic acid and vitamin B6 (source)
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Lowers homocysteine levels, which is associated with cardiovascular disease and stroke (source, source), when taken with folic acid and vitamin B6
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May reduce risk of cognitive decline and Alzheimer’s disease (source)
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Nausea and vomiting
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Diarrhea
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Headache
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Fatigue
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Weakness
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Loss of appetite
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Tingling sensation in the feet or hands
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Redness, swelling, or bruising at the injection site
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Multiple third party studies have shown the health benefits of vitamin B12 and additional clinical trials are ongoing.
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